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International Journal of Oral Implantology



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Int J Oral Implantol (Berl) 11 (2018), Nr. 1     20. Mär. 2018
Int J Oral Implantol (Berl) 11 (2018), Nr. 1  (20.03.2018)

Seite 63-75, PubMed:29557401, Sprache: Englisch

Immediate, early (6 weeks) and delayed loading (3 months) of single, partial and full fixed implant supported prostheses: 1-year post-loading data from a multicentre randomised controlled trial
Mitsias, Miltiadis / Siormpas, Konstantinos / Pistilli, Valeria / Trullenque-Eriksson, Anna / Esposito, Marco
Purpose: To compare the clinical outcome of single, partial and complete fixed implant supported prostheses immediately loaded (within 48 h), early loaded at 6 weeks, and conventionally loaded at 3 months (delayed loading). Materials and methods: A total of 54 patients (18 requiring single implants, 18 partial fixed prostheses, and 18 total fixed cross-arch prostheses) were randomised in equal numbers at two private practices to immediate loading (18 patients), early loading (18 patients), and conventional loading (18 patients) according to a parallel group design with three arms. To be immediately or early loaded, implants had to be inserted with a torque superior to 40 Ncm. Implants were initially loaded with provisional prostheses, replaced after 4 months by definitive ones. Outcome measures were prosthesis and implant failures, complications and peri-implant marginal bone levels. Results: Two conventionally loaded patients rehabilitated with cross-arch fixed total prostheses dropped-out up to 1 year post-loading. No implant or prosthesis failed and three complications occurred, one in each loading group. Peri-implant marginal bone loss was 0.19 ± 0.44 mm at immediately loaded implants, 0.18 ± 0.66 mm at early loaded implants and 0.25 ± 0.28 mm at conventional loaded implants. There were no statistically significant differences in complications (P = 1.000) and bone loss (P = 0.806) between the three loading strategies. Conclusions: All loading strategies were highly successful and no differences could be observed for implant survival and complications when loading implants immediately, early or conventionally.

Conflict of interest statement: This trial was partially funded by MegaGen, the manufacturer of the implants evaluated in this investigation, however data belonged to the authors and by no means did the manufacturer interfere with the conduct of the trial or the publication of its results.

Schlagwörter: Calcium-incorporated titanium, early loading, randomised controlled trial, RBM surface, surface modification
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